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Anthropic released Claude Fable 5.2 and Claude Mythos 5.2 on November 9, 2026, two variants of the same frontier model optimized for advanced technical work. Fable 5.2 is available generally with enhanced cybersecurity and biosecurity restrictions. Mythos 5.2 carries fewer constraints and is restricted to organizations that pass Anthropic's Life Sciences and Cyber Verification Programs. Compliance teams must now account for which variant their organization or vendors can access, and whether internal controls justify that access tier.